I never read any of his novels, but I did have an encounter with Mr. Disch back in the early '90s when I was in publishing. I was talking with him on the phone, trying to get a blurb for a Rachel Pollack novel we were publishing. I was most likely pushing too hard, because the conversation ended with Disch roaring into the phone, "Do you even know who I am?" and hanging up.
Now, you never know what kind of a day someone is having, so I tried not to hold it against him, but I suppose it left a bad enough taste in my mouth that I avoided his novels after that. From what I've heard, it's my loss.